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News 2015

December 31, 2015

The 2015 top ten programming languages. Source:         

December 30, 2015

A reading list to expand your mind (BBC). Source:          

Highlights from 2015 (BBC). Source:         

Practical artificial intelligence tools you can use today. Source:           

Single-molecule detection of contaminants, explosives or diseases now possible. Source:      

December 29, 2015

The top A.I. breakthroughs of 2015. Source:      

How brain architecture relates to consciousness and abstract thoughts. Source:           

December 26, 2015

Opinion Paper: Targeting Multiple Cyclin-Dependent Kinases (CDKs): A New Strategy for Molecular Docking Studies. Source: Current Drug Targets     

December 25, 2015

How to Learn an Algorithm. Source:  

December 23, 2015

New genes associated with extreme longevity identified. Source:  

A ‘garbage disposal’ drug may slow Alzheimer’s and other neurodegenerative diseases. Source:      

Mathematical model for animal stripes. Source:      

December 22, 2015

How to teach machines to see. Source:

Genetic ‘intelligence networks’ discovered in the brain. Source:   

December 21, 2015

AI ‘alarmists’ nominated for 2015 ‘Luddite Award’. Source:    

Magnetic nanoparticles combat biofilms, a source of chronic bacterial infections. Source:     

Deep-learning algorithm predicts photos’ memorability at ‘near-human’ levels. Source:      

December 18, 2015

Scientists blueprint tiny cellular 'nanomachine'. Source:      

December 17, 2015

And Science’s Breakthrough of the Year is... Source:            

NuSTAR finds cosmic clumpy doughnut around black hole. Source:        

December 15, 2015

Importance of physical activity and aerobic exercise for healthy brain function. Source:   

December 14, 2015

New mass spectral imaging instrument maps cells’ composition in 3-D at more than 100 times higher resolution. Source:   

Will this DNA molecular switch replace conventional transistors? Source:     

December 11, 2015

Musk, others commit $1 billion to non-profit AI research company to ‘benefit humanity’. Source:     

December 10, 2015

Periodic table of protein complexes helps predict novel protein structures. Source:   

Worm research in life extension leads scientists to discover new metric to track aging. Source:  

When machines learn like humans. Source:   

Germany fires up bizarre new fusion reactor. Source:   

December 8, 2015

Parkinson’s disease researchers discover a way to reprogram the genome to produce dopamine neurons. Source:   

Can physical activity make you learn better? Source:   

December 7, 2015

Por que a Finlândia está mudando 'um dos melhores sistemas de educação do mundo'?. Source:   

Python 3.5.1 is available for download. Source:  

As the worm turns: research tracks how an embryo’s brain is assembled. Source:   

'Nanobombs’ that blow up cancer cells. Source:      

Hybrid solid-state chips and biological cells integrated at molecular level. Source:      

December 4, 2015

Possible biochemical mechanism underlying long-term memories identified. Source:        

First direct evidence for synaptic plasticity in fruit fly brain. Source:    

December 1, 2015

Do fish have emotions and consciousness? Source:     

November 25, 2015

The hunt for Albert Einstein's missing waves. Source:     

Army ants’ ‘living’ bridges suggest collective intelligence. Source:      

November 24, 2015

Master genetic switch for brain development discovered. Source:     

First real-time imaging of neural activity invented. Source:      

November 20, 2015

A sensory illusion that makes yeast cells self-destruct. Source:    

Researchers discover signaling molecule that helps neurons find their way in the developing brain. Source:          

November 19, 2015

Exercise may protect against neurodegenerative diseases. Source:      

November 17, 2015

Modulating brain’s stress circuity might prevent Alzheimer’s disease. Source:          

Allen Institute researchers decode patterns that make our brains human. Source:    

November 16, 2015

‘Super natural killer cells’ destroy cancer in lymph nodes to halt metastasis. Source:     

Reprogramming neurons and rewiring the brain. Source:   

November 13, 2015

Beyond telomerase: another enzyme discovered critical to maintaining telomere length. Source: 

Experimental drug targeting Alzheimer’s disease shows anti-aging effects. Source:    

IBM’s Watson shown to enhance human-computer co-creativity, support biologically inspired design. Source:   

November 9, 2015

Google open-sources its TensorFlow machine learning system. Source:     

November 3, 2015

Engineers design enhanced magnetic protein nanoparticles to better track cells. Source:     

Semantic Scholar uses AI to transform scientific search. Source:          

First complete pictures of cells’ DNA-copying machinery. Source:          

November 2, 2015

Massive supercomputer simulation models universe from near birth until today. Source:         

Single-agent phototherapy system diagnoses and kills cancer cells. Source:   

How to build a full-scale quantum computer in silicon. Source:     

October 30, 2015

Long-term aerobic exercise prevents age-related brain deterioration. Source:      

October 28, 2015

What happens in the brain when we learn. Source:          

October 26, 2015

A drug-delivery technique to bypass the blood-brain barrier. Source:    

October 24, 2015

A powerful new ‘tool’ for assembling biomolecules. Source:   

October 23, 2015

Processing 3.0.1 is available for download. Source:  

October 22, 2015

Improving learning and memory in aged mice with cholesterol-binding membrane protein. Source:     

Largest astronomical image to date contains 46 billion pixels. Source:     

October 21, 2015

Is your thinking chaotic? There’s a model for that. Source:     

Redesigned Structure Summary Page of Protein Data Bank. Source:

 Comment by Prof. Walter.

 The redesined structure summary page had missing information about ligand-binding affinity. Now they fixed this issue. See e-mails below.

Fwd: Missing binding affinity information in the new version of PDB
De: "Peter Rose" <> para mim - 21/10/2015 16:12

Dear Prof. Filgueira de Azevedo Jr.,

Thank you for reporting the issue. We will fix it with next Wednesday's weekly update.
However, there is a much easier way to retrieve binding affinity information using our RESTful web services.
For example, using our custom report web service, you can retrieve ligand and binding affinity information:,1OHR&customReportColumns=resolution, structureId,chainId,ligandId,ligandMolecularWeight,ligandFormula,ligandName,ligandSmiles,InChIKey,Ki,Kd,EC50,IC50,deltaG,deltaH,deltaS,Ka&service=wsfile&format=csv&ssa=nTo learn more about our web services, please see the following pages:

If you have any question, I'd be happy to do a Skype session and walk you through the details.
Best regards,


Peter Rose, Ph.D.
Site Head, RCSB Protein Data Bank West (
San Diego Supercomputer Center (
University of California, San Diego
---------- Forwarded message ----------

From: "Walter Filgueira de Azevedo Jr." <>
To: <>
Date: Wed, 21 Oct 2015 11:52:50 -0200
Subject: Missing binding affinity information in the new version of PDB

Dear Sir(or Madam),

 Congratulations for the new design of PDB page. It looks great. But, unfortunately a feature related to binding affinity is missing. In the previous version, the HTML code had binding information, for instance IC50. In this new version, I can't find any binding information in the site. I know I can find binding information in another database, for instance, BindingDB, but it seems to me that it is there in the PDB, since it is possible to search at advance search for structures with binding information.
Please, if you have any part of the PDB, that brings this information (IC50, Ki, Kd deltaG) send me the link, and also in which format it was stored. I have been working in the development of a program (, in which one of the features was the download of binding information from the PDB. This information was at
 where XXX is the PDB access code. And it was in HTML format, so it was very useful.
 Thank you very for your time.
 Kind regards,


May 5, 2015

A surprisingly simple bug afflicts computers. Source: