News 2015 

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December 31st, 2015

The 2015 top ten programming languages. Source: spectrum.ieee.org            

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December 30th, 2015

A reading list to expand your mind (BBC). Source: bbc.co.uk          

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December 30th, 2015

Highlights from 2015 (BBC). Source: bbc.co.uk         

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December 30th, 2015

Practical artificial intelligence tools you can use today. Source: Kurzweilai.net           

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December 30th, 2015

Single-molecule detection of contaminants, explosives or diseases now possible. Source: Kurzweilai.net     

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December 29th, 2015

The top A.I. breakthroughs of 2015. Source: Kurzweilai.net      

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December 29th, 2015

How brain architecture relates to consciousness and abstract thoughts. Source: Kurzweilai.net          

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December 26th, 2015

Opinion Paper: Targeting Multiple Cyclin-Dependent Kinases (CDKs): A New Strategy for Molecular Docking Studies. Source: Current Drug Targets     

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December 25th, 2015

How to Learn an Algorithm. Source: Kurzweilai.net  

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December 23rd, 2015

New genes associated with extreme longevity identified. Source: Kurzweilai.net  

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December 23rd, 2015

A ‘garbage disposal’ drug may slow Alzheimer’s and other neurodegenerative diseases. Source: Kurzweilai.net      

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December 23rd, 2015

Mathematical model for animal stripes. Source: www.sciencedaily.com      

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December 22nd, 2015

How to teach machines to see. Source: Kurzweilai.net   

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December 22nd, 2015

Genetic ‘intelligence networks’ discovered in the brain. Source: Kurzweilai.net   

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December 21st, 2015

AI ‘alarmists’ nominated for 2015 ‘Luddite Award’. Source: Kurzweilai.net    

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December 21st, 2015

Magnetic nanoparticles combat biofilms, a source of chronic bacterial infections. Source: Kurzweilai.net     

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December 21st, 2015

Deep-learning algorithm predicts photos’ memorability at ‘near-human’ levels. Source: Kurzweilai.net     

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December 18th, 2015

Scientists blueprint tiny cellular 'nanomachine'. Source: www.sciencedaily.com     

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December 17th, 2015

And Science’s Breakthrough of the Year is... Source: news.sciencemag.org            

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December 17th, 2015

NuSTAR finds cosmic clumpy doughnut around black hole. Source: jpl.nasa.gov       

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December 15th, 2015

Importance of physical activity and aerobic exercise for healthy brain function. Source: Kurzweilai.net   

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December 14th, 2015

New mass spectral imaging instrument maps cells’ composition in 3-D at more than 100 times higher resolution. Source: Kurzweilai.net   

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December 14th, 2015

Will this DNA molecular switch replace conventional transistors? Source: Kurzweilai.net     

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December 11th, 2015

Musk, others commit $1 billion to non-profit AI research company to ‘benefit humanity’. Source: Kurzweilai.net    

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December 10th, 2015

Periodic table of protein complexes helps predict novel protein structures. Source: Kurzweilai.net   

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December 10th, 2015

Worm research in life extension leads scientists to discover new metric to track aging. Source: Kurzweilai.net  

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December 10th, 2015

When machines learn like humans. Source: Kurzweilai.net   

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December 10th, 2015

Germany fires up bizarre new fusion reactor. Source: news.sciencemag.org   

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December 8th, 2015

Parkinson’s disease researchers discover a way to reprogram the genome to produce dopamine neurons. Source: Kurzweilai.net   

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December 8th, 2015

Can physical activity make you learn better? Source: Kurzweilai.net   

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December 7th, 2015

Por que a Finlândia está mudando 'um dos melhores sistemas de educação do mundo'?. Source: bbc.com   

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December 7th, 2015

Python 3.5.1 is available for download. Source: python.org  

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December 7th, 2015

As the worm turns: research tracks how an embryo’s brain is assembled. Source: Kurzweilai.net   

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December 7th, 2015

'Nanobombs’ that blow up cancer cells. Source: Kurzweilai.net      

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December 7th, 2015

Hybrid solid-state chips and biological cells integrated at molecular level. Source: Kurzweilai.net      

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December 4th, 2015

Possible biochemical mechanism underlying long-term memories identified. Source: Kurzweilai.net        

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December 4th, 2015

First direct evidence for synaptic plasticity in fruit fly brain. Source: Kurzweilai.net   

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December 1st, 2015

Do fish have emotions and consciousness? Source: Kurzweilai.net     

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November 25th, 2015

The hunt for Albert Einstein's missing waves. Source: bbc.com     

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November 25th, 2015

Army ants’ ‘living’ bridges suggest collective intelligence. Source: Kurzweilai.net     

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November 24th, 2015

Master genetic switch for brain development discovered. Source: Kurzweilai.net     

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November 24th, 2015

First real-time imaging of neural activity invented. Source: Kurzweilai.net     

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November 20th, 2015

A sensory illusion that makes yeast cells self-destruct. Source: Kurzweilai.net    

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November 20th, 2015

Researchers discover signaling molecule that helps neurons find their way in the developing brain. Source: Kurzweilai.net         

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November 19th, 2015

Exercise may protect against neurodegenerative diseases. Source: Kurzweilai.net      

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November 17th, 2015

Modulating brain’s stress circuity might prevent Alzheimer’s disease. Source: Kurzweilai.net          

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November 17th, 2015

Allen Institute researchers decode patterns that make our brains human. Source: Kurzweilai.net    

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November 16th, 2015

‘Super natural killer cells’ destroy cancer in lymph nodes to halt metastasis. Source: Kurzweilai.net     

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November 16th, 2015

Reprogramming neurons and rewiring the brain. Source: Kurzweilai.net   

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November 13th, 2015

Beyond telomerase: another enzyme discovered critical to maintaining telomere length. Source: Kurzweilai.net 

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November 13th, 2015

Experimental drug targeting Alzheimer’s disease shows anti-aging effects. Source: Kurzweilai.net    

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November 13th, 2015

IBM’s Watson shown to enhance human-computer co-creativity, support biologically inspired design. Source: Kurzweilai.net   

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November 9th, 2015

Google open-sources its TensorFlow machine learning system. Source: Kurzweilai.net    

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November 3rd, 2015

Engineers design enhanced magnetic protein nanoparticles to better track cells. Source: Kurzweilai.net     

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November 3rd, 2015

Semantic Scholar uses AI to transform scientific search. Source: Kurzweilai.net          

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November 3rd, 2015

First complete pictures of cells’ DNA-copying machinery. Source: Kurzweilai.net          

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November 2nd, 2015

Massive supercomputer simulation models universe from near birth until today. Source: Kurzweilai.net         

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November 2nd, 2015

Single-agent phototherapy system diagnoses and kills cancer cells. Source: Kurzweilai.net   

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November 2nd, 2015

How to build a full-scale quantum computer in silicon. Source: Kurzweilai.net     

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October 30th, 2015

Long-term aerobic exercise prevents age-related brain deterioration. Source: Kurzweilai.net      

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October 28th, 2015

What happens in the brain when we learn. Source: Kurzweilai.net          

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October 26th, 2015

A drug-delivery technique to bypass the blood-brain barrier. Source: Kurzweilai.net    

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October 24th, 2015

A powerful new ‘tool’ for assembling biomolecules. Source: Kurzweilai.net   

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October 23rd, 2015

Processing 3.0.1 is available for download. Source: processing.org  

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October 22nd, 2015

Improving learning and memory in aged mice with cholesterol-binding membrane protein. Source: Kurzweilai.net     

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October 22nd, 2015

Largest astronomical image to date contains 46 billion pixels. Source: Kurzweilai.net     

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October 21st, 2015

Is your thinking chaotic? There’s a model for that. Source: Kurzweilai.net    

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October 21st, 2015

Redesigned Structure Summary Page of Protein Data Bank. Source: www.rcsb.org/pdb

 Comment by Prof. Walter.

 The redesined structure summary page had missing information about ligand-binding affinity. Now they fixed this issue. See e-mails below.


Fwd: Missing binding affinity information in the new version of PDB
De: "Peter Rose" <peter.rose@rcsb.org> para mim - 21/10/2015 16:12

Dear Prof. Filgueira de Azevedo Jr.,


Thank you for reporting the issue. We will fix it with next Wednesday's weekly update.
However, there is a much easier way to retrieve binding affinity information using our RESTful web services.
For example, using our custom report web service, you can retrieve ligand and binding affinity information: http://www.rcsb.org/pdb/rest/customReport?pdbids=1SPT,1OHR&customReportColumns=resolution, structureId,chainId,ligandId,ligandMolecularWeight,ligandFormula,ligandName,ligandSmiles,InChIKey,Ki,Kd,EC50,IC50,deltaG,deltaH,deltaS,Ka&service=wsfile&format=csv&ssa=nTo learn more about our web services, please see the following pages:http://www.rcsb.org/pdb/software/wsreport.do
http://www.rcsb.org/pdb/software/rest.do

If you have any question, I'd be happy to do a Skype session and walk you through the details.
Best regards,

Peter

--
Peter Rose, Ph.D.
Site Head, RCSB Protein Data Bank West (http://www.rcsb.org)
San Diego Supercomputer Center (http://bioinformatics.sdsc.edu)
University of California, San Diego
+1-858-822-5497

http://www.rcsb.org/pdb/software/wsreport.do
---------- Forwarded message ----------

From: "Walter Filgueira de Azevedo Jr." <walter@azevedolab.net>
To: <deposit-help@mail.wwpdb.org>
Cc: 
Date: Wed, 21 Oct 2015 11:52:50 -0200
Subject: Missing binding affinity information in the new version of PDB

Dear Sir(or Madam),

 Congratulations for the new design of PDB page. It looks great. But, unfortunately a feature related to binding affinity is missing. In the previous version, the HTML code had binding information, for instance IC50. In this new version, I can't find any binding information in the site. I know I can find binding information in another database, for instance, BindingDB, but it seems to me that it is there in the PDB, since it is possible to search at advance search for structures with binding information.
Please, if you have any part of the PDB, that brings this information (IC50, Ki, Kd deltaG) send me the link, and also in which format it was stored. I have been working in the development of a program (sandres.net), in which one of the features was the download of binding information from the PDB. This information was at http://www.rcsb.org/pdb/explore/explore.do?structureId=XXX
 where XXX is the PDB access code. And it was in HTML format, so it was very useful.
 Thank you very for your time.
 Kind regards,

                    Walter.

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May 5th, 2015

A surprisingly simple bug afflicts computers. Source: bbc.com       

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