Projects

 

 

 

Citation

 

Editorships

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Frontiers Section Editor (Bioinformatics and Biophysics) for the Current Drug Targets ISSN: 1873-5592

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Section Editor (Bioinformatics in Drug Design and Discovery) for the Current Medicinal Chemistry ISSN: 1875-533X

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Member of the Editorial Board for the PeerJ ISSN: 2167-8359

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Member of the Editorial Board for the Current Bioinformatics ISSN: 2212-392X (Online) ISSN: 1574-8936 (Print)

 

Research

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Protein-Ligand Interacions

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Molecular Docking

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Bioinspired Computing

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Computational Systems Biology

 

Recent Publications

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Volkart PA et al. Cyclin-Dependent Kinase 2 in Cellular Senescence and Cancer. A Structural and Functional Review. Curr Drug Targets. 2018.

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de Ávila MB et al.. Structural Basis for Inhibition of Enoyl-[Acyl Carrier Protein] Reductase (InhA) from Mycobacterium tuberculosis. Curr Med Chem 2018.





Aqui temos a disciplina de Biofísica. Nosso foco está na descrição de fenômenos biológicos como a transmissão sináptica com ênfase nas proteínas envolvidas nos processos. Usamos a informação estrutural das proteínas obtidas por meio de cristalografia de difração de raios X. O vídeo ao lado descreve como são realizados experimentos de cristalização de proteínas no espaço.  

Prof. Walter F. de Azevedo Jr., PhD.

Crystallization of protein in a microgravity environment (video in Portuguese). Experiments carried out on the Discovery space shuttle STS-95 on October 29, 1998. 

Video about protein crystallography (Dr. José Henrique Pereira, Molecular Biophysics & Integrated Bioimaging, LBNL, Berkeley, CA, USA).

Pereira JH, de Oliveira JS, Canduri F, Dias MV, Palma MS, Basso LA, Santos DS, de Azevedo WF Jr. Structure of shikimate kinase from Mycobacterium tuberculosis reveals the binding of shikimic acid. Acta Crystallogr D Biol Crystallogr. 2004; 60(Pt 12 Pt 2): 2310-9.

PubMed  PDB