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Citation

 

Editorships

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Frontiers Section Editor (Bioinformatics and Biophysics) for the Current Drug Targets ISSN: 1873-5592

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Section Editor (Bioinformatics in Drug Design and Discovery) for the Current Medicinal Chemistry ISSN: 1875-533X

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Section Editor (Combinatorial/Medicinal Chemistry) for the Combinatorial Chemistry & High Throughput Screening ISSN: 1875-5402

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Member of the Editorial Board for the Current Bioinformatics ISSN: 2212-392X (Online) ISSN: 1574-8936 (Print)

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Member of the Editorial Board for the Organic & Medicinal Chemistry International Journal ISSN: 2474-7610

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Section Editor in Chief (Bioinformatics) for Bioengineering International. ISSN 2668-7119

 

Research

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Protein-Ligand Interacions

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Molecular Docking

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Bioinspired Computing

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Computational Systems Biology

 

Recent Publications

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da Silva AD et al. J Comput Chem. 2020; 41(1): 69-73.

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Volkart PA et al. Curr Drug Targets. 2019;20(7):716-726

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Russo S, De Azevedo WF. Curr Med Chem 2019. 26(10):1908-1919

Astrobiology

Prof. Walter F. de Azevedo, Jr., PhD 

Classes

Materiais      QR Codes
Title: Overview

 

In this course, we present the main concepts of this interdisciplinary science named astrobiology. We study the origin of life on the Earth and take it as a paradigm to investigate the possibility of life in other planets. We start our voyager through astrobiology, describing the beginning of the Universe as predicted by the Big Bang theory. We also study the origin of our Solar System. We investigate the possibility of life on Mars and some moons of outer planets of our Solar System. We describe the exoplanets and the intriguing questions involving the possibility of intelligent life elsewhere in the Universe. Finally, we speculate on the reasons why we weren't able to make contact with extraterrestrial civilizations.

Keywords: Astrobiology; life; the origin of life; extraterrestrial life; Big Bang theory; Solar System; Nasa; Fermi paradox; technological singularity; extraterrestrial intelligence; Mars; Titan; icy bodies in our solar system and beyond; Miller experiment; prebiotic peptides; computational simulations of prebiotic peptides; RNA World; space probes; the search for extraterrestrial intelligence; SETI project; Drake equation; Seager equation.

Title: Big Bang Theory

 

In this class, we will see the fundamentals features of the Big Bang theory. We describe the basics physics of the Bohr's atoms and use it to explain the emission and absorption spectra. We give an overview of the black body radiation and explain how we can use the information about the absorption lines in the stellar spectra to determine the radial velocities of them. We explain the view of the expanding Universe and the Big Bang theory. We show how the stars make heavy elements through nuclear fusion.

Keywords: Astrobiology; Universe; the origin of the Universe; Big Bang theory; electromagnetic spectrum; Bohr's atom; black body radiation; Doppler effect; radial velocity; Voyager probes; Carl Sagan.

Title: The Origin of Our Solar System

 

Planets are necessary for life, as you know. There is speculation also about the possibility of life in moons orbiting planets. In each scenario, we need the existence of a Solar System composed of a stable star and the presence of planets and moons. Here, we'll see the Nebula Hypothesis describing the origin of our Solar System. To clarify all steps involved in the Nebula Hypothesis, we have a glossary of the astronomical objects of this model. We'll discuss the formation of chemical elements inside the stars and also some key features related to the stellar evolution. At the end of our class, we'll describe a tutorial about how to use Publons.

Keywords: Astrobiology; Universe; the origin of our solar system; planets; Nebular Hypothesis; stellar nebula; Eagle Nebula; average star; nuclear fusion; triple alpha; Chandrasekhar limit; massive stars; Sun; red giant; super red giant; planetary nebula; supernova; white dwarf; neutron star; black holes, solar system formation; Publons; h-index; citation metrics.

Here we have the course of astrobiology. In this course, we present the main concepts of this interdisciplinary science named astrobiology. We study the origin of life on the Earth and take it as a paradigm to investigate the possibility of life in other planets. We describe the molecular basis for the origin of life with a focus on nucleic acids and proteins.The main technique used to assess protein structures is the protein crystallography as described in this video on the right. 

Prof. Walter F. de Azevedo Jr., PhD.

Crystallization of protein in a microgravity environment (video in Portuguese). Experiments carried out on the Discovery space shuttle STS-95 on October 29, 1998.

Video about protein crystallography (Dr. José Henrique Pereira, Molecular Biophysics & Integrated Bioimaging, LBNL, Berkeley, CA, USA).

Pereira JH, de Oliveira JS, Canduri F, Dias MV, Palma MS, Basso LA, Santos DS, de Azevedo WF Jr. Structure of shikimate kinase from Mycobacterium tuberculosis reveals the binding of shikimic acid. Acta Crystallogr D Biol Crystallogr. 2004; 60(Pt 12 Pt 2): 2310-9.

PubMed  PDB