Books

 

 

 

Projects

 

 

 

Citation

 

Editorships

Avatar

Frontiers Section Editor (Bioinformatics and Biophysics) for the Current Drug Targets ISSN: 1873-5592

Avatar

Section Editor (Bioinformatics in Drug Design and Discovery) for the Current Medicinal Chemistry ISSN: 1875-533X

Avatar

Section Editor (Combinatorial/Medicinal Chemistry) for the Combinatorial Chemistry & High Throughput Screening ISSN: 1875-5402

Avatar

Member of the Editorial Board for the PeerJ ISSN: 2167-8359

Avatar

Member of the Editorial Board for the Current Bioinformatics ISSN: 2212-392X (Online) ISSN: 1574-8936 (Print)

Avatar

Member of the Editorial Board for the Organic & Medicinal Chemistry International Journal ISSN: 2474-7610

Avatar

Section Editor in Chief (Bioinformatics) for Bioengineering International. ISSN 2668-7119

Avatar

Member of the Editorial Board for the PeerJ Physical Chemistry

 

Research

Avatar

Protein-Ligand Interacions

Avatar

Molecular Docking

Avatar

Bioinspired Computing

Avatar

Computational Systems Biology

 

Recent Publications

Avatar

da Silva AD et al. J Comput Chem. 2020; 41(1): 69-73.

Avatar

Volkart PA et al. Curr Drug Targets. 2019;20(7):716-726

Avatar

Russo S, De Azevedo WF. Curr Med Chem 2019. 26(10):1908-1919

Here, we have the course Discovery and Development of Drugs in Silico. This course focuses on protein structures and their interactions with drugs. The main technique used to assess protein-ligand interactions is the protein crystallography as described in this video on the right. 

Prof. Walter F. de Azevedo Jr., PhD.

Crystallization of protein in a microgravity environment (video in Portuguese). Experiments carried out on the Discovery space shuttle STS-95 on October 29, 1998.

Video about protein crystallography (Dr. José Henrique Pereira, Molecular Biophysics & Integrated Bioimaging, LBNL, Berkeley, CA, USA).

Pereira JH, de Oliveira JS, Canduri F, Dias MV, Palma MS, Basso LA, Santos DS, de Azevedo WF Jr. Structure of shikimate kinase from Mycobacterium tuberculosis reveals the binding of shikimic acid. Acta Crystallogr D Biol Crystallogr. 2004; 60(Pt 12 Pt 2): 2310-9.

PubMed  PDB